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Week 1
Baltimore @ San Francisco (-6)
New England @ Cleveland (-13)
Pittsburgh (-10) @ Cincinnati
Denver @ Houston (-8)
New York (A) @ Kansas City (-2)
Washington @ New York (N) (-16)
Seattle @ Minnesota (-3)
Los Angeles (N) @ Detroit (-1) Game of the week
Chicago @ Arizona (-20)
Dallas (-12) @ Buffalo
Tennessee (-9) @ Miami
Indianapolis @ Los Angeles (A) (-7)
Oakland @ Tampa Bay (-11)
Atlanta @ Carolina (-14)
Philadelphia @ New Orleans (-6)
Jacksonville (-11) @ Green Bay
Week 2
Houston @ Indianapolis (-1)
Arizona @ Dallas (-3)
Chicago @ Green Bay (-1) Game of the week
Tampa Bay (-14) @ Atlanta
Denver @ New England (-1)
Miami @ Buffalo (-2)
Washington @ Carolina (-13)
New Orleans @ Los Angeles (A) (-2)
Oakland (-11) @ Kansas City
Tennessee @ Jacksonville (even)
Minnesota @ Detroit (-1)
New York (N) (-10) @ Philadelphia
Los Angeles (N) @ Pittsburgh (-14)
Cleveland @ Seattle (-2)
Cincinnati @ San Francisco (-4)
New York (A) @ Baltimore (-6)
Week 3
Denver @ Carolina (-18)
Kansas City @ New Orleans (-12)
Los Angeles (A) @ Oakland (-9)
Cleveland (-2) @ Baltimore
Jacksonville (-7) @ Houston
Tennessee (-12) @ Chicago
Indianapolis @ Green Bay (-1) Game of the week
Detroit @ Seattle (-5)
Cincinnati @ Los Angeles (N) (-5)
Minnesota @ San Francisco (-2)
Pittsburgh @ Arizona (-5)
New York (A) @ New England (-1)
New York (N) (-9) @ Miami
Dallas (-13) @ Atlanta
Philadelphia @ Tampa Bay (-19)
Washington @ Buffalo (-3)
Week 4
Chicago @ Detroit (-5)
Minnesota @ Los Angeles (N) (-3)
Houston @ Oakland (-11)
Arizona (-10) @ Seattle
Dallas (-12) @ Washington
Jacksonville (-5) @ Los Angeles (A)
Indianapolis @ Tennessee (-18)
Carolina (-13) @ Kansas City
Tampa Bay (-18) @ Denver
Baltimore (-2) @ New England Game of the week
Buffalo @ Miami (-4)
Green Bay @ Philadelphia (-7)
Atlanta @ New Orleans (-7)
New York (N) (-15) @ New York (A)
Cincinnati @ Cleveland (-6)
San Francisco @ Pittsburgh (-15)
Week 5
Baltimore @ Cleveland (-8)
Kansas City @ Oakland (-17)
New Orleans @ Carolina (-10)
Los Angeles (A) (-4) @ Denver
Buffalo @ Jacksonville (-13)
Houston @ Chicago (-1)
Green Bay @ Tennessee (-20)
Detroit @ Indianapolis (-1) Game of the week
Seattle @ Cincinnati (-1)
Los Angeles (N) @ San Francisco (-2)
Arizona (-10) @ Minnesota
New England @ Pittsburgh (-23)
Miami (-3) @ New York (A)
New York (N) @ Dallas (-5)
Atlanta @ Tampa Bay (-20)
Washington @ Philadelphia (-3)
Week 6
New Orleans @ Tampa Bay (-16)
Oakland (-10) @ Denver
Kansas City @ Los Angeles (A) (-11)
Seattle @ Washington (-1)
Chicago @ Indianapolis (-3)
Philadelphia @ Dallas (-18)
Cleveland @ Houston (even)
Jacksonville @ Tennessee (-6)
Green Bay @ Minnesota (-9)
San Francisco @ Detroit (-2)
Pittsburgh (-15) @ New York (A)
Carolina @ New York (N) (-6)
Los Angeles (N) @ Atlanta (even) Game of the week
Arizona (-14) @ Baltimore
Buffalo (-4) @ New England
Miami @ Cincinnati (-2)
Week 7
Jacksonville (-12) @ Denver
Tennessee (-16) @ Kansas City
Dallas (-14) @ Chicago
Seattle (-3) @ Green Bay
Minnesota @ Houston (-1)
Cleveland @ Pittsburgh (-13)
Philadelphia (-2) @ New York (A)
Oakland (-2) @ New Orleans
Tampa Bay @ Arizona (-2)
Miami @ Baltimore (even) Game of the week
Cincinnati @ Buffalo (-3)
New England @ Indianapolis (-8)
Los Angeles (A) @ Carolina (-11)
Atlanta @ New York (N) (-17)
San Francisco @ Los Angeles (N) (-4)
Washington @ Detroit (-3)
Week 8
Jacksonville (-9) @ Indianapolis
Tampa Bay (-11) @ Los Angeles (A)
Houston (-3) @ Kansas City
Seattle @ Los Angeles (N) (-3)
San Francisco @ Arizona (-17)
Atlanta @ Philadelphia (-4)
Denver @ Oakland (-16)
Baltimore @ Pittsburgh (-18)
Green Bay @ Chicago (-5)
Cleveland @ Cincinnati (even) Game of the week
Detroit @ New Orleans (-6)
Dallas (-2) @ Carolina
New York (A) @ Buffalo (-8)
Miami (-5) @ New England
New York (N) (-10) @ Washington
Minnesota @ Tennessee (-14)
Week 9
Carolina @ Oakland (-1)
Jacksonville (-5) @ Minnesota
Atlanta (-2) @ Kansas City
New York (A) @ Miami (-9)
New York (N) @ Tampa Bay (-6)
Philadelphia @ Washington (-3)
Indianapolis @ Denver (even) Game of the week
Cincinnati @ Los Angeles (A) (-5)
Cleveland @ Arizona (-15)
Baltimore @ Los Angeles (N) (-7)
Buffalo @ Pittsburgh (-16)
Dallas (-19) @ New England
New Orleans @ Seattle (-2)
Green Bay @ San Francisco (-8)
Detroit @ Chicago (-1)
Houston @ Tennessee (-16)
Week 10
Pittsburgh @ Tennessee (-3)
New York (A) @ Washington (-8)
Oakland (-7) @ Indianapolis
Philadelphia @ Miami (-4)
Buffalo @ Cleveland (-6)
Los Angeles (A) @ Atlanta (even)
Baltimore @ Denver (even)
Green Bay @ Houston (-7)
Detroit @ Arizona (-18)
Los Angeles (N) @ Seattle (-3)
San Francisco @ Chicago (even) Game of the week
Carolina (-5) @ Minnesota
Cincinnati (-4) @ New England
Dallas @ New York (N) (-1)
Tampa Bay (-10) @ New Orleans
Kansas City @ Jacksonville (-19)
Week 11
Kansas City @ Indianapolis (-7)
New Orleans @ Washington (even) Game of the week
Buffalo @ New York (N) (-16)
Cleveland (-5) @ New York (A)
Pittsburgh (-9) @ Miami
New England @ Philadelphia (-10)
Tampa Bay @ Dallas (-2)
Tennessee (-2) @ Oakland
Carolina (-8) @ Atlanta
Denver @ Los Angeles (A) (-10)
Cincinnati @ Baltimore (-1)
Houston @ Jacksonville (-13)
Green Bay @ Detroit (-7)
Arizona (-10) @ Los Angeles (N)
Seattle @ San Francisco (-2)
Chicago @ Minnesota (-7)
Week 12
Arizona (-12) @ Cincinnati
Seattle (-1) @ Baltimore
Cleveland @ Miami (-1)
Houston (-2) @ New York (A)
Los Angeles (N) (-1) @ Chicago Game of the week
New York (N) (-9) @ San Francisco
Dallas (-12) @ Philadelphia
Washington (-4) @ New England
Oakland @ Pittsburgh (-8)
New Orleans (-1) @ Atlanta
Los Angeles (A) @ Buffalo (-1)
Detroit @ Jacksonville (-13)
Tennessee (-12) @ Indianapolis
Minnesota (-3) @ Green Bay
Denver @ Kansas City (-2)
Carolina @ Tampa Bay (-9)
Week 13
New England @ New York (A) (-5)
Indianapolis @ Minnesota (-7)
San Francisco @ Carolina (-12)
New Orleans (-5) @ Denver
Kansas City @ Cleveland (-12)
Baltimore @ Buffalo (-5)
Tampa Bay (-13) @ Washington
Philadelphia @ New York (N) (-16)
Miami @ Dallas (-17)
Atlanta @ Oakland (-12)
Los Angeles (A) @ Tennessee (-14)
Chicago @ Jacksonville (-15)
Houston @ Detroit (-3) Game of the week
Seattle @ Arizona (-16)
Cincinnati @ Pittsburgh (-16)
Green Bay @ Los Angeles (N) (-9)
Week 14
Carolina (-7) @ Philadelphia
Pittsburgh (-8) @ Seattle
Minnesota (-1) @ Chicago Game of the week
Denver @ Tennessee (-21)
Los Angeles (A) @ Houston (-1)
Los Angeles (N) @ Cleveland (-4)
Detroit (-1) @ Green Bay
Arizona (-11) @ San Francisco
Washington @ Atlanta (-2)
Miami @ Oakland (-10)
Indianapolis @ Baltimore (-3)
Buffalo (-2) @ New York (A)
New England @ New York (N) (-23)
New Orleans @ Dallas (-15)
Kansas City @ Tampa Bay (-25)
Jacksonville (-7) @ Cincinnati
Week 15
Indianapolis @ Houston (-5)
New York (A) @ Dallas (-23)
Arizona (-16) @ Green Bay
Chicago @ Tampa Bay (-21)
Denver @ Atlanta (-7)
New England @ Buffalo (-10)
Miami @ Washington (-2) Game of the week
Carolina (-4) @ New Orleans
Los Angeles (A) (-5) @ Kansas City
Oakland @ Jacksonville (-5)
Tennessee (-10) @ Detroit
Minnesota @ New York (N) (-14)
Philadelphia @ Los Angeles (N) (-5)
Pittsburgh (-7) @ Cleveland
San Francisco @ Seattle (-4)
Baltimore @ Cincinnati (-5)
Week 16
Oakland (-3) @ Los Angeles (A)
Washington @ Dallas (-18)
Chicago @ Seattle (-7)
Tennessee (-10) @ Houston
Detroit @ Minnesota (-5)
Los Angeles (N) @ Arizona (-16)
Tampa Bay (-3) @ Carolina
Kansas City @ Denver (-4)
Indianapolis @ Jacksonville (-15)
New England @ Miami (-11)
Buffalo @ Philadelphia (-3)
Atlanta @ Green Bay (even) Game of the week
New York (N) (-7) @ New Orleans
New York (A) @ Cincinnati (-8)
San Francisco @ Cleveland (-5)
Pittsburgh (-12) @ Baltimore